Merus’s Zenocutuzumab market size expected to increase many folds by 2032, report DelveInsight

Zenocutuzumab Drug Market Forecast and Analysis

DelveInsight has recently published a report on “Zenocutuzumab Market Forecast Report” providing an in-depth analysis of the Zenocutuzumab market analysis and forecasts up to 2032 in the seven major markets (7MM) (i.e. the United States, EU4 (Germany, France, Italy, and Spain), the United Kingdom, and Japan. The comprehensive report provides an analysis of Zenocutuzumab market potential and market share analysis in the Rare NRG1 Fusion therapeutics space across the 7MM from 2019 to 2032. 

The report also helps you to understand the Zenocutuzumab clinical and commercial developments along with parameters like the drug’s Mechanism of Action (MOA), Route of Administration (ROA), dosage, and special designations.

Interested in finding out the projected market size of Zenocutuzumab by 2032? Visit:Zenocutuzumab Market Forecast

Zenocutuzumab Drug Summary

Zenocutuzumab (MCLA-128) is an IgG1 bispecific antibody being developed by Merus. It blocks the action of the growth factor NRG1, a protein that can be overproduced due to NRG1 fusions, and prohibits it from binding to HER3. HER3 is a protein that sits on the surface of cancer cells, and when it combines with a second surface protein, HER2, it sends signals to drive tumor growth and survival. NRG1 induces the combination of HER2 and HER3.

Zenocutuzumab is a bispecific antibody, i.e., it can recognize two different proteins, specifically HER2 and HER3. It is designed to have a dock and block mechanism. First, zenocutuzumab (MCLA-128) docks onto HER2. Which then leads to blocking HER3’s ability to bind NRG1. In addition to its direct action on the cancer cell linking to HER2 and HER3, zenocutuzumab (MCLA-128) is manufactured in a way that aims to increase a patient’s own ability to attack cancer, called antibody-dependent cell-mediated cytotoxicity (ADCC) properties. Zenocutuzumab (MCLA-128) possesses enhanced ADCC activity (NRG1, n.d.).

Enrollment continues in the eNRGy trial of Zeno monotherapy in NRG1+ cancer and in a Phase II trial of Zeno in combination with androgen deprivation therapy (ADT) in castration resistant prostate cancer (CRPC) and in combination with afatinib in NRG1+ non-small-cell lung cancer (NSCLC).

In October 2022, Merus met with the US Food and Drug Administration (FDA) regarding a potential biologics license application (BLA) filing for Zeno in NRG1+ cancer. Based on the FDA’s feedback, Merus believes multiple registrational paths remain viable and has decided the optimal approach is to sequence its development plan by first seeking a potential application for NRG1+ lung and/or pancreatic cancer, which could then be followed by a potential tissue agnostic filing. The company believes Zeno has the potential to be both first in class and best in class and a new standard of care for the treatment of NRG1+ cancer.

Stay ahead of the competition by leveraging key insights and evolving trends in the Zenocutuzumab Market @ Zenocutuzumab Market Outlook and Key Assessment

Key Highlights of the Zenocutuzumab Market Report

• The report contains forecasted sales evaluation of Zenocutuzumab for Rare NRG1 Fusion till 2032.
• It provides comprehensive coverage of late-stage emerging therapies for Rare NRG1 Fusion treatment.
• The report also features qualitative and quantitative analysis with analysts, as well as KOL views for Zenocutuzumab in Rare NRG1 Fusion.

Why Zenocutuzumab Market Report?

• Leading Zenocutuzumab for Rare NRG1 Fusion forecasted market data will support the clients in the decision-making process regarding their therapeutic portfolio by identifying the overall scenario of the Zenocutuzumab.
• A thorough Zenocutuzumab market forecast will help understand how the drug is competing with other emerging therapies in the therapeutics landscape.
• It will help to get an analysis of the Zenocutuzumab clinical trial advancements and the detailed clinical assessment, regulatory, and commercial assessment
• The report also provides future market assessments for Zenocutuzumab market for Rare NRG1 Fusion in the 7 Major Markets, advanced qualitative analysis like SWOT, expert analysts’ views, a detailed overview of market competitors, and a short analysis of other emerging therapies in Rare NRG1 Fusion.

Download the sample report to learn more about the evolving market dynamics @ Zenocutuzumab Market Trends and Key Developments

Related Reports By DelveInsight:

Rare NRG1 Fusion Market Outlook and Forecast

“Rare NRG1 Fusion Market Insights, Epidemiology and Market Forecast 2032” report delivers an in-depth understanding of Rare NRG1 Fusion, historical and forecasted epidemiology as well as the Rare NRG1 Fusion market trends in the United States, EU4 (Germany, Spain, Italy, and France), and the United Kingdom, and Japan. It also covers the key companies and emerging therapies in the Rare NRG1 Fusion therapeutics landscape.

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